COMPARATIVE EVALUATION OF DIFFERENT WOUND DRESSINGS IN HEALING CHRONIC ULCERS: A RANDOMIZED CONTROLLED TRIAL
Abstract
Background: Chronic ulcers pose significant challenges in wound management, often requiring various wound dressings to promote effective healing. This randomized controlled trial aims to compare the efficacy of different wound dressings in healing chronic ulcers.
Materials and Methods: Thirty patients with chronic ulcers were randomly assigned to three groups: Group A received Hydrocolloid dressings, Group B received Alginate dressings, and Group C received Foam dressings. The study spanned 12 weeks, during which wound measurements, pain assessments, and wound tissue analyses were conducted at regular intervals.
Results: After 12 weeks, Group A showed an average reduction of ulcer size by 65% (p < 0.05), Group B exhibited a reduction of 58% (p < 0.05), and Group C demonstrated a reduction of 53% (p < 0.05). Pain scores decreased significantly in all groups (Group A: 3.2 to 1.1, Group B: 3.4 to 1.2, Group C: 3.5 to 1.3, p < 0.05). Histological analysis revealed improved granulation tissue formation and decreased inflammation in all groups, with Group A showing the most substantial improvements.
Conclusion: Hydrocolloid, Alginate, and Foam dressings all exhibited effectiveness in promoting healing of chronic ulcers. However, Hydrocolloid dressings demonstrated the highest reduction in ulcer size, pain scores, and improved histological markers. The choice of wound dressing should be based on individual patient needs and wound characteristics.
